Open AccessComparative study of histopathological Marsh grading with clinical and serological parameters in celiac iceberg of north India
Author(s) -
Shivani Kalhan,
Preeti Joseph,
Sonia Sharma,
Suparna Dubey,
Sharmila Dudani,
Monika Dixit
Publication year - 2011
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.81593
Subject(s) - serology , grading (engineering) , iceberg , medicine , marsh , veterinary medicine , geography , biology , immunology , ecology , wetland , antibody , sea ice , meteorology
Celiac disease is an autoimmune disorder caused by the ingestion of wheat gluten and related proteins in genetically susceptible individuals. It is characterized by anti-tissue transglutaminase (anti-tTG) antibodies. Duodenal biopsy is the gold standard for diagnosis. Correlation of clinical, serologic, and histological features is essential for a definitive diagnosis. The ratio of diagnosed versus undiagnosed cases is quite high.