Open AccessImmunohistochemical phospho tensin tumor suppressor gene staining patterns in endometrial hyperplasias: A 2-year study
Author(s) -
Anjali Rao,
Garima Arya,
Padmapriya Jaiprakash
Publication year - 2011
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.81588
Subject(s) - pten , tensin , atypia , pathology , medicine , endometrial hyperplasia , malignancy , immunohistochemistry , carcinoma , hyperplasia , exact test , biology , apoptosis , biochemistry , pi3k/akt/mtor pathway
Endometrial carcinoma is a common neoplasm associated with the female genital tract with considerable morbidity. Endometrial hyperplasias have been widely regarded as precursor lesions. It is of importance to the pathologist to identify the subset of hyperplasias or the associated factor which could be a possible forerunner of malignancy. Phospho tensin gene (PTEN) has gained importance as one of the factors responsible.