Naturally occurring anti M complicating ABO grouping | Zendy

Safoorah Khalid | Zendy; Roelyn Dantes | Zendy; Sunu Varghese | Zendy; Imadeddin Al Hakawati | Zendy

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Naturally occurring anti M complicating ABO grouping

Author(s) -

Safoorah Khalid,

Roelyn Dantes,

Sunu Varghese,

Imadeddin Al Hakawati

Publication year - 2011

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/0377-4929.77394

Subject(s) - abo blood group system , clinical significance , blood grouping , antibody , blood bank , interpretation (philosophy) , medicine , immunology , pathology , philosophy , emergency medicine , linguistics

Anti M is considered a naturally occurring antibody that is usually active at temperatures below 37°C and is thus of no clinical significance. This antibody, if present in an individual, can lead to a discrepancy between forward and reverse ABO grouping and thus creates diagnostic difficulties for blood bank staff. We report a case of a 58-year-old lady who had an unexpected reaction in reverse grouping due to anti M that posed a problem for us in the interpretation of results of her blood group. We also reviewed the literature to find out the significance of such discrepancy in blood grouping.

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