Open AccessEmbryonal rhabdomyosarcoma of the adult soft palate
Author(s) -
Samar Bhutoria,
Ciaran ONeil
Publication year - 2011
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.77367
Subject(s) - embryonal rhabdomyosarcoma , rhabdomyosarcoma , myogenin , desmin , pathology , sarcoma , medicine , biology , anatomy , immunohistochemistry , skeletal muscle , vimentin , myogenesis
Embryonal rhabdomyosarcoma is the most common soft tissue sarcoma in children. We report a rare case of embryonal rhabdomyosarcoma of the soft palate in a 32-year-old Caucasian female. Detailed histology of the tumor is described. Positive staining with desmin, myogenin and myoD1 confirmed the tumor to be embryonal rhabdomyosarcoma. A genetic association between rhabdomyosarcoma, polycystic ovary syndrome and the FEM1A gene on the human chromosome is speculated upon.