Open AccessMatrix metalloproteinases 2 and 9 in situ mRNA expression in colorectal tumors from Iraqi patients
Author(s) -
Mohanad Mohsin Ahmed,
Suhad Hadi Mohammed
Publication year - 2011
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.77316
Subject(s) - in situ hybridization , matrix metalloproteinase , in situ , context (archaeology) , confidence interval , adenocarcinoma , statistical significance , biopsy , resection margin , medicine , pathology , messenger rna , resection , biology , chemistry , cancer , surgery , paleontology , biochemistry , organic chemistry , gene
Matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9) preferentially degrade the basement membrane, a key step in tumor invasion, metastases, and induction of vascularization of tumor tissue.