Primary epithelioid angiosarcoma of bone: A case report with immunohistochemical study | Zendy

Ranjini Kudva | Zendy; Shahin Perveen | Zendy; Janardhana P Aithala | Zendy

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Primary epithelioid angiosarcoma of bone: A case report with immunohistochemical study

Author(s) -

Ranjini Kudva,

Shahin Perveen,

Janardhana P Aithala

Publication year - 2010

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/0377-4929.72103

Subject(s) - medicine , angiosarcoma , pathology , primary bone , immunohistochemistry , osteosarcoma , chemotherapy , pleural effusion , epithelioid cell , neoplasm

Primary malignant vascular tumors of the bone are exceedingly rare and represent <1% of primary malignant bone tumors. Angiosarcoma is a malignant mesenchymal neoplasm in which the neoplastic cells demonstrate endothelial differentiation. Epithelioid angiosarcoma (EA) is a rare variant of angiosarcoma that is characterized by large cells with an epithelioid morphology. EA is an aggressive tumor with poor prognosis. Here, we present a case of a 62-year-old man who had primary EA of the left tibia. He was treated with amputation and chemotherapy. After 1 month of chemotherapy, he developed pleural effusion and died.

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