Open AccessBenign metastasizing leiomyoma
Author(s) -
Saira Fatima,
Zubair Ahmed,
Mohammad Azam
Publication year - 2010
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - Uncategorized
Resource type - Journals
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.72099
Subject(s) - leiomyoma , histopathology , pathology , medicine , stain , smooth muscle , uterine leiomyoma , cd34 , pleural effusion , immunohistochemistry , smooth muscle tumor , hysterectomy , uterine fibroids , radiology , biology , staining , stem cell , genetics
Benign metastasizing leiomyoma (BML) is a rare condition, affecting predominantly reproductive-age females with uterine leiomyomata and is most often associated with multiple benign-appearing smooth muscle tumors in lungs. We report herein a case of a 38-year-old woman who presented with multiple uterine fibroids for which hysterectomy was carried out on her. Postoperatively, she developed left-sided pleural effusion. Computed chest tomography (CT) scan revealed multiple nodules in both lungs and pleurae. Histopathology of one of the pleura-based nodules revealed a neoplasm composed of interlacing fascicles of spindle cells with uniform nuclei. The tumor cells were positive for alpha-smooth muscle actin and negative for CD34 immunohistochemical stain.