Open AccessNonspecificity of 35 kDa protein: A proposed marker for the differential diagnosis of M. avium infection in the Indian population
Author(s) -
Kapil Gupta,
R. C. Mahajan,
G. K. Khuller,
Indu Verma
Publication year - 2010
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.72053
Subject(s) - antibody , antigen , mycobacterium tuberculosis , tuberculosis , population , gel electrophoresis , blot , protein subunit , biology , monoclonal antibody , microbiology and biotechnology , virology , medicine , immunology , gene , pathology , biochemistry , environmental health
The subunit vaccine strategies and development of various diagnostic reagents for Mycobacterium avium infection relies on the presence of secreted, species-specific mycobacterial antigens. The M. avium 35 kDa protein has been suggested as a candidate for vaccine/diagnostic reagent, specifically for M. avium infection. The present study was conducted to evaluate the diagnostic specificity of the M. avium 35 kDa protein in the Indian population.