Open AccessApoptosis of peripheral blood mononuclear cells in patients with sepsis
Author(s) -
Zohreh Jadali,
Mohammad Mehdi Amiri,
Massoud Ravanbakhsh
Publication year - 2010
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.72013
Subject(s) - peripheral blood mononuclear cell , apoptosis , tumor necrosis factor alpha , annexin , sepsis , immunology , in vivo , medicine , necrosis , pathogenesis , context (archaeology) , biology , in vitro , flow cytometry , biochemistry , paleontology , microbiology and biotechnology
Recent investigations into the pathogenesis of sepsis reveal an important role for apoptosis. The present study was designed in order to assess the peripheral blood mononuclear cells' (PBMCs) apoptosis and the plasma levels of molecules associated with apoptosis belonging to tumor necrosis factor-alpha (TNF-α)/tumor necrosis factor type-1 receptor (TNFR I) pathway in patients with sepsis.