Open AccessOsseous metaplasia and mature bone formation with extramedullary hematopoiesis in follicular adenoma of thyroid gland
Author(s) -
Harsh Mohan,
Parul Dimri,
Nitin M. Nagarkar
Publication year - 2009
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.54999
Subject(s) - extramedullary hematopoiesis , thyroid , pathology , metaplasia , medicine , adenoma , calcification , follicular phase , dystrophic calcification , haematopoiesis , endocrinology , biology , stem cell , genetics
Follicular adenomas of the thyroid may be subjected to degenerative changes like hemorrhagic and cystic changes, fibrosis, and calcification. Mature bone formation is a rare phenomenon, but extramedullary hematopoiesis (EMH) has also been rarely reported in thyroid gland. The combination of mature bone formation and EMH is rarer and has been reported, in a single case report, in a multinodular goitre. We describe a case of follicular adenoma with histologically proven osseous metaplasia and mature bone formation with EMH in a middle- aged woman, which, to our knowledge, is the first case in English language literature.