Hemophagocytic syndrome: A cause for fatal outcome in tuberculosis | Zendy

AnupamaP Gupta | Zendy; SN Parate | Zendy; S. K. Bobhate | Zendy; Anupriya Anupriya | Zendy

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Hemophagocytic syndrome: A cause for fatal outcome in tuberculosis

Author(s) -

AnupamaP Gupta,

SN Parate,

S. K. Bobhate,

Anupriya Anupriya

Publication year - 2009

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/0377-4929.48939

Subject(s) - hepatosplenomegaly , phagocytosis , haematopoiesis , medicine , bone marrow , immunology , tuberculosis , generalized lymphadenopathy , lymphoma , pathology , biology , stem cell , disease , genetics

Hemophagocytic syndrome is rare syndrome characterized by unregulated proliferation and activation of macrophages and phagocytosis of the platelet, erythrocytes, lymphocytes and their hematopoietic precursors in the bone marrow, resulting in cytopenias. It is associated with stimuli-like infections, malignancies and immunocompromised states. We present here a case of generalized lymphadenopathy, hepatosplenomegaly and progressive cytopenias in a 17-year-old male.

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