Open AccessImmunohistochemical distinction between mesothelial and adenocarcinoma cells in serous effusions: A combination panel-based approach with a brief review of the literature
Author(s) -
Paari Murugan,
Neelaiah Siddaraju,
Syed Habeebullah,
Debdatta Basu
Publication year - 2009
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.48910
Subject(s) - serous fluid , carcinoembryonic antigen , immunohistochemistry , pathology , immunostaining , medicine , calretinin , adenocarcinoma , cytology , serous membrane , stain , vimentin , antigen , staining , cancer , immunology
The prognostic and therapeutic significance of differentiating adenocarcinoma (AC) from reactive mesothelium (RM) in effusions cannot be overemphasized. To avoid diagnostic errors, ancillary techniques like immunohistochemistry are employed. However, results vary and no universal standard has been accepted so far.