Anaplastic large-cell lymphoma with florid granulomatous reaction: A case report and review of literature | Zendy

Srinivasan Balamurugan | Zendy; B Rajasekar | Zendy; R. Rao | Zendy

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Anaplastic large-cell lymphoma with florid granulomatous reaction: A case report and review of literature

Author(s) -

Srinivasan Balamurugan,

B Rajasekar,

R. Rao

Publication year - 2009

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/0377-4929.44969

Subject(s) - medicine , lymphoma , anaplastic large cell lymphoma , pathology , granuloma , biopsy , lymph node biopsy , lymph node , generalized lymphadenopathy , immunohistochemistry , granulomatous disease , histiocyte , dermatology , disease

Granulomatous reactions have been reported in association with lymphomas, more often with Hodgkins disease than with Non-Hodgkins Lymphoma. Not many reports are available on the association of anaplastic large-cell lymphoma with sarcoid-type granuloma. Herein, we report a case of an elderly female with generalized lymphadenopathy who had a florid granulomatous reaction almost masking the lymphoma cells in the lymph node biopsy. A detailed clinical history, careful histological examination and immunohistochemistry helped in attaining the correct diagnosis.

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