Open AccessAnaplastic large-cell lymphoma with florid granulomatous reaction: A case report and review of literature
Author(s) -
S. Balamurugan,
B Rajasekar,
Ramesh Rao
Publication year - 2009
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.44969
Subject(s) - medicine , lymphoma , anaplastic large cell lymphoma , pathology , granuloma , biopsy , lymph node biopsy , lymph node , generalized lymphadenopathy , immunohistochemistry , granulomatous disease , histiocyte , dermatology , disease
Granulomatous reactions have been reported in association with lymphomas, more often with Hodgkins disease than with Non-Hodgkins Lymphoma. Not many reports are available on the association of anaplastic large-cell lymphoma with sarcoid-type granuloma. Herein, we report a case of an elderly female with generalized lymphadenopathy who had a florid granulomatous reaction almost masking the lymphoma cells in the lymph node biopsy. A detailed clinical history, careful histological examination and immunohistochemistry helped in attaining the correct diagnosis.