Open AccessNodular regenerative hyperplasia of liver
Author(s) -
Divya Shelly,
Tevatia,
Ashok Kumar Praharaj,
Anurag Mehta,
Srinivasan Harish,
Baskaran Vasudevan
Publication year - 2008
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.40408
Subject(s) - nodular regenerative hyperplasia , medicine , portal hypertension , liver parenchyma , hyperplasia , parenchyma , pathology , biopsy , liver biopsy , gastroenterology , cirrhosis
Nodular regenerative hyperplasia of the liver (NRHL) is a very rare cause of portal hypertension and liver failure. The condition is characterized by diffuse micronodular transformation of hepatic parenchyma without fibrous septa between the nodules. We present our experience with a 32-year-old woman who presented with recurrent episodes of upper gastrointestinal bleeding associated with massive splenomegaly who was subsequently found to have NRHL. This article considers the salient aspects of this rare condition, how it affects the patients and the options available in its management. A plea is made for the need for liver biopsy for all patients with portal hypertension especially those being considered for surgery.