Open AccessImmunohistochemistry in surgical pathology practice: A current perspective of a simple, powerful, yet complex, tool
Author(s) -
Nirmala A. Jambhekar,
Anshuman Chaturvedi,
Bhulaxmi Madur
Publication year - 2008
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.40382
Subject(s) - comparability , immunohistochemistry , perspective (graphical) , quality assurance , medicine , pathology , surgical pathology , medical physics , computer science , artificial intelligence , external quality assessment , mathematics , combinatorics
Immunohistochemistry (IHC) is a powerful tool in the surgical pathologists' armamentarium. The requests for IHC and the list of monoclonal antibodies have increased tremendously in the past decade. Issues concerning technical reproducibility, uniformity of interpretation, inter-laboratory comparability, and quality assurance are assuming greater importance due to the increased availability of IHC and its impact on diagnosis and therapy. An attempt has been made to give a current perspective of this simple and yet, in some aspects, a complex tool.