Open AccessThe absence of CD56 expression can differentiate papillary thyroid carcinoma from other thyroid lesions
Author(s) -
Ioana Golu,
Mihaela Vlad,
Alis Dema,
Lavinia Cristina Moleriu,
Anca Tudor,
Mihaela Iacob,
Oana Popa,
Mărioara Cornianu
Publication year - 2017
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.208378
Subject(s) - thyroid , pathology , thyroid carcinoma , medicine , follicular phase , immunohistochemistry , thyroiditis , follicular cell , hyperplasia
The neural cell adhesion molecule CD56 is an antigen important for the differentiation of the follicular epithelium. Recent studies have reported low or absent expression of CD56 in papillary thyroid carcinoma (PTC) and its presence in normal thyroid tissue, benign thyroid lesions, and most follicular non-PTC tumors.