Open AccessImpact of methylene blue staining in the retrieval of lymph nodes in resected colorectal cancer specimens
Author(s) -
Vasala Anjaneyulu,
HaripreethaG Nair,
SubramanyeshwarT Rao,
K Ravindranath Tagore,
Sudha Murthy,
Daphne Fonseca
Publication year - 2016
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.191804
Subject(s) - lymph , colorectal cancer , methylene blue , medicine , lymph node , stage (stratigraphy) , staining , oncology , pathology , cancer , biology , paleontology , biochemistry , photocatalysis , catalysis
Adequate lymph node harvest in resected colorectal cancer (CRC) specimens is important in staging and choosing appropriate therapeutic options. The yield of lymph nodes and metastatic nodes by methylene blue dye injection in 30 randomly selected resected CRC specimens was compared with an equal number of CRC specimens (control) with matched grade and stage.The mean number of lymph nodes retrieved in the study group was 22 ± 9 compared to 17 ± 8 in the control group which was statistically significant (P = 0.04).Methylene blue technique is an effective aid in increasing the yield of lymph nodes in the resected CRC specimens.