Do phosphatase of regenerating liver-3, matrix metalloproteinases-2, matrix metalloproteinases-9, and epidermal growth factor receptor-1 predict response to therapy and survival in glioblastoma multiforme? | Zendy

Nuzhat Husain | Zendy; Priyanka Soni | Zendy; Anil Chandra | Zendy; Bal Krishna Ojha | Zendy; MadanLal Brahma Bhatt | Zendy; Rakesh Kumar Gupta | Zendy

Open Access

Do phosphatase of regenerating liver-3, matrix metalloproteinases-2, matrix metalloproteinases-9, and epidermal growth factor receptor-1 predict response to therapy and survival in glioblastoma multiforme?

Author(s) -

Nuzhat Husain,

Priyanka Soni,

Anil Chandra,

Bal Krishna Ojha,

MadanLal Brahma Bhatt,

Rakesh Kumar Gupta

Publication year - 2016

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/0377-4929.188121

Subject(s) - epidermal growth factor receptor , univariate analysis , context (archaeology) , medicine , immunohistochemistry , matrix metalloproteinase , radiation therapy , survival analysis , proportional hazards model , oncology , epidermal growth factor , pathology , multivariate analysis , cancer , receptor , biology , paleontology

Poor survival of the glioblastoma multiforme (GBM) has been attributed in part to the invasive nature of the lesion making complete surgical removal near impossible. Phosphatase of regenerating liver-3 (PRL-3), matrix metalloproteinases-2 and -9 (MMP-2 and MMP-9), and epidermal growth factor receptor (EGFR-1) play a role in invasive nature of tumor cells.

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