Open AccessSignificance of fibrotic bands in utero - Amniotic band sequence with limb body wall complex: A rare case of fetal autopsy
Author(s) -
Pooja Devi,
P J Cicy,
Renu Thambi,
Usha Poothiode
Publication year - 2015
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.168876
Subject(s) - amniotic band , amniotic band syndrome , congenital talipes equinovarus , gastroschisis , fetus , medicine , anatomy , amnion , autopsy , clubfoot , abdominal wall defect , arthrogryposis , gestation , in utero , placenta , amniotic fluid , abdominal wall , pathology , pregnancy , surgery , biology , deformity , genetics
Amniotic band sequence (ABS) includes a wide spectrum of abnormalities resulting from entrapment of various fetal parts from a disrupted amnion, ranging from a mere constriction ring affecting a finger to a fatal form called limb body wall complex (LBWC). Reported cases of ABS with LBWC are very few. The spectrum of anomalies depends on which part gets entrapped and at what point of gestation. Hence, the clinical presentation can be extremely variable. Early detection of such cases using sonology is really challenging due to the small size of the fibrotic bands. Here, we present a case of amniotic band syndrome with LBWC in a fetus at 24 weeks of gestation, which was referred for an autopsy. The fetus also showed scoliosis, gastroschisis, lumbosacral meningocele, congenital talipes equinovarus, and cleft palate, thus having features of placenta cranial and placenta abdominal phenotype which is very rare.