Chlamydia pneumoniae-related hemophagocytic lymphohistiocytosis in an adult patient with clonal karyotype abnormality | Zendy

TzuChuan Huang | Zendy; ZhengYi Huang | Zendy; Tzong-Shi Chieuh | Zendy; Kwei-Shuai Hwang | Zendy

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Chlamydia pneumoniae-related hemophagocytic lymphohistiocytosis in an adult patient with clonal karyotype abnormality

Author(s) -

TzuChuan Huang,

ZhengYi Huang,

Tzong-Shi Chieuh,

Kwei-Shuai Hwang

Publication year - 2015

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/0377-4929.162928

Subject(s) - hemophagocytic lymphohistiocytosis , pneumonia , immunology , karyotype , chlamydia , medicine , chlamydiaceae , abnormality , disease , biology , pathology , chromosome , gene , genetics , psychiatry

Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease characterized by a severe hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and macrophages. Herein, we report a 58-year-old male who had Chlamydia pneumoniae-related pneumonia, followed by aggressive HLH. An abnormal cytogenetic profile was also detected. To our knowledge, this is the first report of an adult patient with C. pneumonia-associated HLH.

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