BRAF, KIT, NRAS, GNAQ and GNA11 mutation analysis in cutaneous melanomas in Turkish population | Zendy

İsmail Yılmaz | Zendy; Mehmet Gamsızkan | Zendy; Zafer Küçükodacı | Zendy; Dilaver Demırel | Zendy; Aptullah Haholu | Zendy; Gizem Narlı | Zendy; Ufuk Berber | Zendy

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BRAF, KIT, NRAS, GNAQ and GNA11 mutation analysis in cutaneous melanomas in Turkish population

Author(s) -

İsmail Yılmaz,

Mehmet Gamsızkan,

Zafer Küçükodacı,

Dilaver Demırel,

Aptullah Haholu,

Gizem Narlı,

Ufuk Berber

Publication year - 2015

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/0377-4929.162831

Subject(s) - gnaq , neuroblastoma ras viral oncogene homolog , exon , mutation , cancer research , medicine , sanger sequencing , population , melanoma , genetics , biology , gene , kras , environmental health

KIT and mitogen-activated protein kinase cascade are important for melanomagenesis. In the present study, we analyzed the frequency of BRAF, NRAS, KIT, GNAQ and GNA11 gene mutations and investigated their association with clinicopathological features of melanomas in Turkish population.

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