Flow cytometric analysis of Mixed phenotype acute leukemia: Experience from a tertiary oncology center | Zendy

RekhaA Nair | Zendy; PriyaMary Jacob | Zendy; Kunjulekshmi AmmaRaveendran Nair Anila | Zendy; Shruti Prem | Zendy; Rajeswary Binitha | Zendy; Parukuttyamma Kusumakumary | Zendy; Renu Sukumaran | Zendy

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Flow cytometric analysis of Mixed phenotype acute leukemia: Experience from a tertiary oncology center

Author(s) -

RekhaA Nair,

PriyaMary Jacob,

Kunjulekshmi AmmaRaveendran Nair Anila,

Shruti Prem,

Rajeswary Binitha,

Parukuttyamma Kusumakumary,

Renu Sukumaran

Publication year - 2015

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/0377-4929.155309

Subject(s) - immunophenotyping , acute leukemia , medicine , leukemia , myeloid leukemia , myeloid , immunology , antigen

Mixed phenotype acute leukemia (MPAL) is a rare subset of acute leukemia where the blasts exhibit lineage specific antigens of more than one lineage. Flow cytometric immunophenotyping is essential for the diagnosis of MPAL and the accurate diagnosis highly depends on the panel of markers used. The precise incidence of MPAL is uncertain as various institutions use different combinations of antibodies to assign the blasts to a particular lineage.

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