Open AccessGranulosa cell tumor of testis: Clinicopathological correlation of a rare tumor
Author(s) -
Swapnil Rane,
Santosh Me,
Sangeeta Desai,
Ganesh Bakshi,
Amit Joshi
Publication year - 2014
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.142665
Subject(s) - granulosa cell , pathology , immunohistochemistry , leydig cell tumor , biology , ovarian tumor , stromal cell , ovary , medicine , leydig cell , ovarian cancer , cancer , hormone , endocrinology , luteinizing hormone
Granulosa cell tumor of testis is a rare tumor accounting for less than 4% of adult testicular tumors though they account for nearly 30% of childhood testicular tumors. Due to the rarity of these tumors, exact etiology, pathogenesis, prognostic factors and best treatment approach are not well known. The molecular events in pathogenesis of these stromal tumors have begun to unravel and these developments put forth a reasonable and scientific explanation for the association of these tumors with developmental anomalies like undescended testis. However, many questions remain unanswered.