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Aggressive natural killer-cell leukemia: Classical presentation of a rare disease
Author(s) -
RekhaA Nair,
PriyaM Jacob,
Anila KunjulekshmiAmma Raveendran Nair
Publication year - 2014
Publication title -
indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.138787
Subject(s) - hepatosplenomegaly , jaundice , medicine , bone marrow , disease , leukemia , natural history , rare disease , presentation (obstetrics) , neoplasm , pathology , immunology , surgery
Aggressive natural killer-cell leukaemia is a rare aggressive form of natural killer-cell neoplasm. We report a case of a 40-year-old male who presented with jaundice, raised blood counts,generalised lymphadenopathy and hepatosplenomegaly. The diagnosis was established by flow cytometric analysis of bone marrow aspirate. The patient, however, succumbed to his illness within 2 weeks of starting chemotherapy. To the best of our knowledge, this is the third reported case from India.

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