Open AccessCytokeratin expression in gastrointestinal stromal tumors: Morphology, meaning, and mimicry
Author(s) -
Yetish Sing,
Pratistadevi K. Ramdial,
Amsha Ramburan,
Vikash Sewram
Publication year - 2014
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.134665
Subject(s) - cytokeratin , pdgfra , pathology , biology , stromal cell , gist , immunohistochemistry , medicine
Gastrointestinal stromal tumors (GISTs) are biologically distinctive neoplasms harboring KIT and PDGFRA mutations. Cytokeratin expression in GISTs is an under-recognized diagnostic pitfall, especially in high grade GISTs with limited biopsy material and from metastatic sites.