Open AccessInter-observer agreement in reporting HER 2 Neu protein over expression by immunohistochemistry
Author(s) -
Ibrahim Al Haddabi,
Asim Qureshi,
Anna Saparamadu,
Aisha Al Hamdani,
Marwa Al Riyami,
Shyam S. Ganguly
Publication year - 2014
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.134663
Subject(s) - medicine , kappa , tertiary care , concordance , immunohistochemistry , reproducibility , h&e stain , cohen's kappa , pathology , statistics , mathematics , geometry
HER 2 Neu protein overexpression and its detection by immunohistochemistry (IHC) has become quiet critical because of its relevance in regards to Herceptin treatment. This peer review was done at a tertiary care center, which aimed at determining the inter-observer variation among five pathologists and evaluating the degree of agreement between them.