Open AccessTuberculous neuritis: A rare sequel of a common disease
Author(s) -
Bhushan M. Warpe,
Sandhya V Poflee,
Nandu P Pande,
Alka Shrikhande
Publication year - 2014
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.130902
Subject(s) - medicine , ethambutol , neuritis , rifampicin , tuberculosis , leprosy , peripheral neuropathy , streptomycin , mycobacterium tuberculosis , dermatology , disease , nerve biopsy , surgery , pathology , antibiotics , microbiology and biotechnology , biology , diabetes mellitus , endocrinology
Tuberculosis (TB), a disease caused by Mycobacterium tuberculosis is an infectious disease that continues to be a significant health problem in a developing country like India. The cause of peripheral neuropathy associated with tuberculosis is controversial. Possibilities include the toxic effects of anti-tuberculous chemotherapy (especially, rifampicin, streptomycin & ethambutol), immune mediated neuropathy, direct invasion of nerves, vasculitic neuropathy, compressive neuropathy, and meningitic reaction. This report describes an unusual finding of tuberculous granulomas in the peripheral nerve (Greater auricular nerve) of a patient ,who presented with a painful neck swelling. Granulomas were present in Greater auricular nerve (C2,C3) biopsy specimen associated with tuberculous peri-neuritis, but with no more specific indications of the mechanism of the neuropathy.