Open AccessHeparin: Induced thrombocytopenia: Incidence and laboratory approach to diagnosis in Indians
Author(s) -
Jyoti Kotwal,
Sanjeev Chaudhary,
Manoj Gopal Madakshira,
Shahbaz Hasnain,
Velu Nair,
M Luthra
Publication year - 2014
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.130886
Subject(s) - heparin induced thrombocytopenia , heparin , medicine , incidence (geometry) , platelet factor 4 , platelet , population , surgery , gastroenterology , physics , environmental health , optics
One of the most common complications of heparin administration is heparin-induced thrombocytopenia (HIT) which can also lead to catastrophic thrombotic events. The problem of identifying the cause of thrombocytopenia, as due to heparin, in patients with multiple co-morbid conditions is very essential for management. Thus, the laboratory investigations for diagnosis of HIT play a pivotal role. The objective of the study was to arrive at the incidence of HIT in ethnic Indian population and provide a decision after analysis of tests used to diagnose HIT.