The correlation between p16 expression and INK4a locus mutation with grades and stages in oral squamous cell carcinoma | Zendy

Sareh Farhadi | Zendy; Bahram Kazemi | Zendy; MohammadJavad Kharazifard | Zendy; Mojgan Bandehpour | Zendy; Soudabeh Sargolzaei | Zendy

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The correlation between p16 expression and INK4a locus mutation with grades and stages in oral squamous cell carcinoma

Author(s) -

Sareh Farhadi,

Bahram Kazemi,

MohammadJavad Kharazifard,

Mojgan Bandehpour,

Soudabeh Sargolzaei

Publication year - 2014

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/0377-4929.130877

Subject(s) - locus (genetics) , basal cell , correlation , microbiology and biotechnology , epidermoid carcinoma , gene , polymerase chain reaction , lymph node , carcinoma , tumor suppressor gene , biology , cancer research , medicine , pathology , genetics , carcinogenesis , geometry , mathematics

p16INK4a is a tumor suppressor gene playing a critical role. Researches have indicated the gene to be altered in oral squamous cell carcinoma. Present studies have tried to assess the correlation between p16INK4a expression and INK4a locus mutation in relation to grades and stages of this tumor.

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