Open AccessOrbital solitary fibrous tumor with multinucleate giant cells: Case report of an unusual finding in an uncommon tumor
Author(s) -
Kaustubh Mulay,
Santosh G Honavar
Publication year - 2013
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.120399
Subject(s) - giant cell , cd34 , cd68 , pathology , solitary fibrous tumor , multinucleate , differential diagnosis , mediastinum , soft tissue , anatomy , medicine , immunohistochemistry , biology , stem cell , microbiology and biotechnology
Solitary fibrous tumor (SFT) is a rare soft-tissue neoplasm which may occur at any site although it is more frequent in the pleura, mediastinum and lung. Orbital involvement by SFT is uncommon. Giant cells are extremely rare to be seen in a SFT and have been described to be immunoreactive for CD34. We present a case of orbital SFT with multinucleate giant cells expressing CD68 and lacking immunoreactivity for CD34. The differential diagnosis is discussed.