Inhibiting valosin-containing protein suppresses osteosarcoma cell metastasis via AKT/nuclear factor of kappa B signaling pathway in vitro | Zendy

Zhili Liu | Zendy; Shan-Hu Huang | Zendy; Qingfeng Luo | Zendy; Zhihong Zhang | Zendy; Xinhua Long | Zendy

Open Access

Inhibiting valosin-containing protein suppresses osteosarcoma cell metastasis via AKT/nuclear factor of kappa B signaling pathway in vitro

Author(s) -

Zhili Liu,

Shan-Hu Huang,

Qingfeng Luo,

Zhihong Zhang,

Xinhua Long

Publication year - 2013

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/0377-4929.120358

Subject(s) - protein kinase b , cancer research , gene silencing , metastasis , western blot , phosphorylation , kinase , microbiology and biotechnology , chemistry , medicine , biology , cancer , biochemistry , gene

The strategies of targeting valosin-containing protein (VCP) may have therapeutic potential for treating cancer metastasis. In this study, we aim to investigate the correlation of VCP protein expression in osteosarcoma (OS) tissues with pulmonary metastasis and its possible molecular mechanism.

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