Open AccessPlacental mesenchymal dysplasia: A report of two cases with review of literature
Author(s) -
S Sheeja,
Usha Poothiode,
Mohan P Shiny,
Renu Thambi
Publication year - 2013
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.116153
Subject(s) - medicine , placenta , dysplasia , mesenchymal stem cell , obstetrics , fetus , pregnancy , pathology , biology , genetics
Placental mesenchymal dysplasia (PMD) is a recently recognized, rare placental vascular anomaly characterized by placentomegaly and grape-like vesicles mimicking partial molar pregnancy. It is associated with significant fetal morbidity and mortality. We describe the histologic features of PMD in two different cases with different disease outcomes, one in a preterm intrauterine death (IUD) and another in a live birth. Placental examination in both the cases revealed large placenta with multiple vesicles and mesenchymal dysplasia.