Open AccessIntensive method of assessment and classification of the bone marrow iron status: A study of 80 patients
Author(s) -
Rajeshwari S Bableshwar,
Mousumi Roy,
Akshay Bali,
Pradeep S Patil,
Suvarna Inumella
Publication year - 2013
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.116142
Subject(s) - bone marrow , medicine , pathology
The increasing prevalence of multiple co-morbidities among anemic patients with chronic diseases have made the use of serum ferritin (which is also an acute phase reactant) and transferrin saturation more challenging in diagnosing iron deficiency. Microscopic examination of bone marrow aspirate is the gold standard" for assessing marrow iron store. However, conventional Gale's method assesses iron in marrow fragments alone which provides little valuable information about functional iron deficiency seen in many chronic diseases.