Open AccessA 60-year-old lady with leonine facies: A rare diagnosis
Author(s) -
Deepti Mutreja,
Abhishek Purohit,
Pawan Kumar Singh,
Haraprasad Pati
Publication year - 2012
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.107824
Subject(s) - infiltration (hvac) , medicine , systemic mastocytosis , biopsy , pathology , skin biopsy , facies , dermatology , bone marrow , geology , paleontology , physics , structural basin , thermodynamics
Systemic mastocytosis is a rare clonal disorder characterized by mast cell infiltration of one or more organs, with or without skin involvement. Leonine facies is a rare presentation and corresponds to the morphologic manifestation of diffuse dermal infiltration of the face as a result of long standing disease. Bone marrow aspiration and biopsy findings in a 60-year-old woman, who had extensive cutaneous infiltration due to systemic mastocytosis, resulting in 'leonine facies,' are described, and causes of leonine facies are discussed.