Open AccessMycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient
Author(s) -
Somdatta Patra,
Mukul Vij,
B. Sukanya,
Dharmesh Kapoor
Publication year - 2012
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.107792
Subject(s) - mycophenolate , medicine , diarrhea , adverse effect , inflammatory bowel disease , colitis , gastroenterology , disease , liver disease , liver transplantation , graft versus host disease , toxicity , transplantation
Mycophenolate mofetil (MMF) is a commonly used immunosuppressive drug in the management of transplant recipients. Gastrointestinal (GI) toxicity (diarrhea) is the most frequently reported adverse event in MMF-treated transplant patients. MMF-induced Graft versus Host Disease has rarely been reported in literature. We report a case of MMF-induced colitis with Graft versus Host Disease-like features, to highlight the importance of high clinical suspicion for its diagnosis, and that appropriate management in such a setting can reduce morbidity and mortality. We also review the relevant literature.