Open AccessEfficacy and Safety of Unmanipulated Haploidentical Related Donor Allogeneic Peripheral Blood Stem Cell Transplantation in Patients with Relapsed/Refractory Acute Myeloid Leukemia
Author(s) -
Liping Dou,
Honghua Li,
Lu Wang,
Fēi Li,
Wenrong Huang,
Li Yu,
DaiHong Liu
Publication year - 2018
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.4103/0366-6999.228243
Subject(s) - medicine , cumulative incidence , transplantation , myeloid leukemia , refractory (planetary science) , incidence (geometry) , granulocyte colony stimulating factor , gastroenterology , leukemia , surgery , chemotherapy , physics , astrobiology , optics
Studies of haploidentical-related donor (HRD) stem cell transplantation using a combination of peripheral blood stem cells (PBSCs) and bone marrow as the graft have reported encouraging results for patients with hematological diseases. However, few studies specifically reported transplantation of only PBSCs from HRDs among patients with relapsed or refractory acute myeloid leukemia (AML). Here, the long-term outcomes and side effects of unmanipulated HRD PBSC transplantation (HRD-PBSCT) for relapsed/refractory AML were analyzed.