Open AccessLikelihood ratios: Clinical application in day-to-day practice
Author(s) -
Rajul Parikh,
Shefali Parikh,
Ellen Arun,
Ravi Thomas
Publication year - 2009
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/0301-4738.49397
Subject(s) - medicine , odds , odds ratio , medical diagnosis , diagnostic odds ratio , likelihood ratios in diagnostic testing , statistics , pre and post test probability , confidence interval , logistic regression , mathematics , pathology
In this article we provide an introduction to the use of likelihood ratios in clinical ophthalmology. Likelihood ratios permit the best use of clinical test results to establish diagnoses for the individual patient. Examples and step-by-step calculations demonstrate the estimation of pretest probability, pretest odds, and calculation of posttest odds and posttest probability using likelihood ratios. The benefits and limitations of this approach are discussed.