Open AccessRetinal toxicity of intravitreally injected plain and liposome formulation of fluconazole in rabbit eye
Author(s) -
Thirumurthy Velpandian,
K. Narayanan,
Tapas Chandra Nag,
A. Ravi,
Suresh Gupta
Publication year - 2006
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/0301-4738.27947
Subject(s) - medicine , rabbit (cipher) , fluconazole , ophthalmology , toxicity , pharmacology , antifungal , dermatology , statistics , mathematics
Candidal endophthalmitis is a sight-threatening ocular infection that most frequently occurs as a complication of candidemia. Fluconazole has been effective against Candida albicans in various animal models. Our objective was to evaluate retinal toxicity of plain and liposome formulation of fluconazole at various dose levels after intravitreal injection.