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Paraneoplastic retinopathy associated with occult bladder cancer
Author(s) -
M Nivean,
Danson Vasanthan Muttuvelu,
Pia Afzelius,
Dalia Cecilia Berman
Publication year - 2016
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/0301-4738.181744
Subject(s) - medicine , occult , malignancy , retinopathy , fluorescein angiography , cancer , radiology , positron emission tomography , bladder cancer , carcinoma , erg , ophthalmology , pathology , visual acuity , diabetes mellitus , retinal , alternative medicine , endocrinology
The aim was to report the first case of cancer-associated retinopathy (CAR) presenting before bladder cancer diagnosis. A 71-year-old woman with a history of bilateral vision loss underwent subsequent complete ophthalmic examination include a fluorescein angiography, full-field electroretinogram (ERG), serology including serum antibodies for CAR, and positron emission tomography-computed tomography (PET-CT) scan. The patient was diagnosed with bladder carcinoma revealed by PET-CT. Timely recognition of this entity may be crucial for an increased patient survival thus adult onset progressive photoreceptor dysfunction, confirmed by ERG, should alert to a possible remote effect of known or occult malignancy. In the latter, PET-CT may be exploited as a powerful diagnostic tool.

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