Open AccessCD4+ T Lymphocytes count in sickle cell anaemia patients attending a tertiary hospital
Author(s) -
Omotola Toyin Ojo,
Wuraola A. Shokunbi
Publication year - 2014
Publication title -
nigerian medical journal/nigerian medical journal
Language(s) - English
Resource type - Journals
eISSN - 2229-774X
pISSN - 0300-1652
DOI - 10.4103/0300-1652.132058
Subject(s) - medicine , asymptomatic , immunology , immune system , lymphocyte , sickle cell anemia , hematology , cellular immunity , cell , disease , anemia , gastroenterology , biology , genetics
Sickle cell haemoglobin (HbS) is the commonest abnormal haemoglobin and it has a worldwide distribution. Reports have shown that patients with sickle cell anaemia (HbSS) have an increased susceptibility to infection leading to increased morbidity and mortality. Impaired leucocyte function and loss of both humoral and cell-mediated immunity are some of the mechanisms that have been reported to account for the immunocompromised state in patients with sickle cell disease. This study was carried out to determine the CD4+ T lymphocytes count in patients with sickle cell anaemia.