Open AccessCurrent role of dexmedetomidine in clinical anesthesia and intensive care
Author(s) -
Manpreet Kaur,
Preet Mohinder Singh
Publication year - 2011
Publication title -
al-banǧ. maqālāt wa abḥāṯ fī al-taẖdīr wa-al-in’āš
Language(s) - English
Resource type - Journals
ISSN - 0259-1162
DOI - 10.4103/0259-1162.94750
Subject(s) - dexmedetomidine , medicine , sedation , sedative , anesthesia , delirium , perioperative , agonist , intensive care , medetomidine , analgesic , intensive care medicine , receptor , blood pressure , heart rate
Dexmedetomidine is a new generation highly selective α2-adrenergic receptor (α2-AR) agonist that is associated with sedative and analgesic sparing effects, reduced delirium and agitation, perioperative sympatholysis, cardiovascular stabilizing effects, and preservation of respiratory function. The aim of this review is to present the most recent topics regarding the advantages in using dexmedetomidine in clinical anesthesia and intensive care, while discussing the controversial issues of its harmful effects.