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Effect of magnesium sulfate and clonidine in attenuating hemodynamic response to pneumoperitoneum in laparoscopic cholecystectomy
Author(s) -
Yatish Bevinaguddaiah,
ShruthiP Kamble,
DineshChillkunda Nagaraja,
VinayakS Pujar,
TejeshC Anandaswamy
Publication year - 2017
Publication title -
anesthesia essays and researches
Language(s) - English
Resource type - Journals
ISSN - 0259-1162
DOI - 10.4103/0259-1162.200228
Subject(s) - pneumoperitoneum , medicine , clonidine , anesthesia , hemodynamics , saline , magnesium , blood pressure , haemodynamic response , mean arterial pressure , heart rate , surgery , laparoscopy , chemistry , organic chemistry
Pneumoperitoneum in laparoscopic procedures is associated with hemodynamic response, due to the release of catecholamines and vasopressin. Magnesium and clonidine have been used to attenuate such hemodynamic responses by inhibiting release of these mediators. We conducted this randomized, double-blinded study to assess which of the two attenuates hemodynamic response better.

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