Open AccessEffect of magnesium sulfate and clonidine in attenuating hemodynamic response to pneumoperitoneum in laparoscopic cholecystectomy
Author(s) -
Shruthi P Kamble,
Yatish Bevinaguddaiah,
Dinesh Chillkunda Nagaraja,
Vinayak S Pujar,
Tejesh C Anandaswamy
Publication year - 2017
Publication title -
al-banǧ. maqālāt wa abḥāṯ fī al-taẖdīr wa-al-in’āš
Language(s) - English
Resource type - Journals
ISSN - 0259-1162
DOI - 10.4103/0259-1162.200228
Subject(s) - pneumoperitoneum , hemodynamics , clonidine , anesthesia , medicine , saline , magnesium , blood pressure , mean arterial pressure , haemodynamic response , heart rate , surgery , laparoscopy , chemistry , organic chemistry
Pneumoperitoneum in laparoscopic procedures is associated with hemodynamic response, due to the release of catecholamines and vasopressin. Magnesium and clonidine have been used to attenuate such hemodynamic responses by inhibiting release of these mediators. We conducted this randomized, double-blinded study to assess which of the two attenuates hemodynamic response better.