Open AccessPalonosetron and granisetron in postoperative nausea vomiting: A randomized double-blind prospective study
Author(s) -
Amrita Anil Gugale,
Pradnya M Bhalerao
Publication year - 2016
Publication title -
al-banǧ. maqālāt wa abḥāṯ fī al-taẖdīr wa-al-in’āš
Language(s) - English
Resource type - Journals
ISSN - 0259-1162
DOI - 10.4103/0259-1162.191121
Subject(s) - palonosetron , granisetron , medicine , postoperative nausea and vomiting , anesthesia , antiemetic , nausea , vomiting , randomized controlled trial , surgery
Postoperative nausea and vomiting (PONV) is a common occurrence after laparoscopic surgeries. A number of pharmacological agents (antihistamines, butyrophenones, dopamine receptor antagonists) have been tried of which the 5-hydroxytryptamine type 3 receptor antagonists are devoid of most side effects and highly effective in prevention and treatment of PONV. Thus, we evaluated the effectiveness of granisetron and palonosetron in prevention of PONV after laparoscopic surgeries under general anesthesia.