Open AccessComparative evaluation of dexmedetomidine and clonidine with low dose ropivacaine in cervical epidural anesthesia for modified radical mastectomy: A prospective randomized, double-blind study
Author(s) -
Shivakumar M Channabasappa,
Gopinath H Venkatarao,
Shobha Girish,
Nandakishore K Lahoti
Publication year - 2016
Publication title -
al-banǧ. maqālāt wa abḥāṯ fī al-taẖdīr wa-al-in’āš
Language(s) - English
Resource type - Journals
ISSN - 0259-1162
DOI - 10.4103/0259-1162.167844
Subject(s) - dexmedetomidine , ropivacaine , clonidine , medicine , anesthesia , modified radical mastectomy , randomized controlled trial , prospective cohort study , mastectomy , surgery , sedation , breast cancer , cancer
Alpha-2 adrenergic agonists clonidine and dexmedetomidine, are well known to produce analgesia through an opioid independent mechanism. Alpha-2 agonists are used as an adjuvant to local anesthetic agents to extend the duration of spinal, epidural and brachial plexus blocks.