
Comparative analysis of efficacy of lignocaine 1.5 mg/kg and two different doses of dexmedetomidine (0.5 μg/kg and 1 μg/kg) in attenuating the hemodynamic pressure response to laryngoscopy and intubation
Author(s) -
Michell Gulabani,
Pavan Gurha,
Prashant Dass,
Nishi Kulshreshtha
Publication year - 2015
Publication title -
al-banǧ. maqālāt wa abḥāṯ fī al-taẖdīr wa-al-in’āš
Language(s) - English
Resource type - Journals
ISSN - 0259-1162
DOI - 10.4103/0259-1162.150167
Subject(s) - dexmedetomidine , anesthesia , medicine , laryngoscopy , context (archaeology) , intubation , hemodynamics , blood pressure , saline , heart rate , sedation , paleontology , biology
Laryngoscopy and intubation cause an intense reflex increase in heart rate, blood pressure, due to an increased sympathoadrenal pressor response. Lignoocaine has shown blunting of pressor response to intubation. Dexmedetomidine has sympatholytic effects.