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Comparison between dexmedetomidine and midazolam premedication in pediatric patients undergoing ophthalmic day-care surgeries
Author(s) -
Deepal Prajapati,
Shailesh Bhadla,
Thaju Louis,
Garima Puri,
Saurin B Panchal,
Mayur Bhuva
Publication year - 2013
Publication title -
anesthesia essays and researches
Language(s) - English
Resource type - Journals
ISSN - 0259-1162
DOI - 10.4103/0259-1162.118982
Subject(s) - dexmedetomidine , premedication , midazolam , anesthesia , medicine , sedation , clonidine , shivering , placebo , alternative medicine , pathology
Midazolam is the most commonly used premedication in children. It has been shown to be more effective than parental presence or placebo in reducing anxiety and improving compliance at induction of anesthesia. Clonidine, an a2 agonist, has been suggested as an alternative. Dexmedetomidine is a more a2 selective drug with more favorable pharmacokinetic properties than clonidine.

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