Open AccessConsequences of hypoxia-reoxygenation phenomena in patients with obstructive sleep apnea syndrome
Author(s) -
Tansu Ulukavak Çiftçi,
Oğuz Köktürk,
Senay Demirtas,
Özlem Gülbahar,
Neslihan Bukan
Publication year - 2011
Publication title -
annals of saudi medicine/annals of saudi medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.373
H-Index - 44
eISSN - 0975-4466
pISSN - 0256-4947
DOI - 10.4103/0256-4947.75772
Subject(s) - obstructive sleep apnea , medicine , sleep medicine , polysomnography , hypoxia (environmental) , sleep apnea , apnea , pediatrics , sleep disorder , psychiatry , insomnia , chemistry , organic chemistry , oxygen
Obstructive sleep apnea syndrome (OSAS) is a common disorder characterized by numerous episodes of absence of respiratory flow during sleep, which can be followed by a decrease in SaO2, which is rapidly normalized when ventilation resumes. We hypothesize that this hypoxia-reoxygenation phenomena may affect the generation of vascular endothelial growth factor (VEGF), erythropoietin (EPO), endothelin-1 (ENDO-1), and inducible nitric oxide synthase (iNOS).