Open AccessAntidepressant-like activity of anthocyanidins from Hibiscus rosa-sinensis flowers in tail suspension test and forced swim test
Author(s) -
Pallavi B Shewale,
Rupali A Patil,
Yogesh A Hiray
Publication year - 2012
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.99303
Subject(s) - tail suspension test , behavioural despair test , prazosin , serotonergic , imipramine , pharmacology , chemistry , haloperidol , dopaminergic , hypoactivity , antidepressant , antagonist , serotonin , dopamine , endocrinology , medicine , receptor , biochemistry , alternative medicine , pathology , hippocampus
Flowers of Hibiscus rosa-sinensis Linn (Malvaceae) popularly known as "China-rose flowers" contain flavonoids. Flavonoids have been found to have antidepressant activity. The aim of the present study is to evaluate the antidepressant activity of flavonoids in H. rosa-sinensis flowers with possible involvement of monoamines.