Open AccessEffect of beta-1-blocker, nebivolol, on central aortic pressure and arterial stiffness in patients with essential hypertension
Author(s) -
S. Radhika,
M. U. R. Naidu,
Sree Bhushan Raju,
A. Krishna Prasad,
T Ramesh Kumar Rao
Publication year - 2012
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.96349
Subject(s) - nebivolol , medicine , pulse wave velocity , blood pressure , cardiology , arterial stiffness , pulse pressure , essential hypertension , aortic pressure , peripheral , heart rate
Blood pressure (BP) reduction is the major determinant of benefit provided by antihypertensive treatment. Although different drugs reduce peripheral BP to some extent, there may be a significant difference in their effect on central BP reduction. It has been shown that beta-blockers are efficient in reducing peripheral, but not central BP. This study was done to assess the effect of beta-1-blocker, nebivolol, in patients with essential hypertension on central aortic pressures and arterial stiffness.