Open AccessCarbamazepine-induced hepato-splenomegaly with erythematous rashes in a child
Author(s) -
Apoorva Mittal,
Somnath Das
Publication year - 2012
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.93868
Subject(s) - carbamazepine , medicine , incidence (geometry) , dermatology , drug reaction , adverse effect , adverse drug reaction , drug , skin reaction , antiepileptic drug , pharmacology , anesthesia , epilepsy , psychiatry , physics , optics
Carbamazepine is an antiepileptic drug. In clinical trials the total incidence of reported adverse reaction to this drug is 4.5 per million at defined daily doses, corresponding to 2.7 per million at prescribed daily doses. Among the adverse reactions of carbamazepine, most often reported are skin reactions (48%), hematological (14%), hepatic disorder (10%). Herein, we present a case with erythematous skin rashes and hepato-splenomegaly.